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Enhancing Federal Clean Energy Innovation - Board On Energy And Environmental Systems - Bog - National Academies Press - Plusbog.dk

Enhancing Federal Clean Energy Innovation - Board On Energy And Environmental Systems - Bog - National Academies Press - Plusbog.dk

A widespread and rapid transition to a low-carbon energy system by 2050 is essential to keep pace with ambitious policy goals and avoid the worst consequences of climate change. Innovation is necessary to lower costs and improve performance of existing technologies and to develop new clean energy options that address challenges in harder-to-decarbonize sectors. To examine means by which the U.S. federal government can rise to this challenge, the National Academies of Sciences, Engineering, and Medicine hosted a virtual workshop series "Enhancing Federal Clean Energy Innovation" on July 27 to August 7, 2020. The workshop featured timely, action-orientated assessments of how to strengthen development and penetration of new clean energy technologies. This publication summarizes the presentations and discussions that occurred over the course of the workshop. Table of ContentsFront MatterOverview1 The Imperative to Accelerate Energy Innovation2 Strategies for Acceleration: Strengthening User Pull3 Strategies for Acceleration: Leveraging and Learning from the Department of Defense4 Managing the Department of Energy's Research and Development Portfolio5 Expert Roundtable6 Advanced Manufacturing and the Climate Crisis: Changes and Opportunities7 Thinking Globally8 Next StepsAppendixesAppendix A: Statement of TaskAppendix B: Workshop AgendaAppendix C: Planning Committee and Participant Biographical InformationAppendix D: Registered Workshop ParticipantsAppendix E: Acronyms

DKK 370.00
1

Accelerating the Development of New Drugs and Diagnostics - Development Forum On Drug Discovery - Bog - National Academies Press - Plusbog.dk

Accelerating the Development of New Drugs and Diagnostics - Development Forum On Drug Discovery - Bog - National Academies Press - Plusbog.dk

Advances in technologies and knowledge are creating new avenues for research and opportunities for the discovery and clinical development of innovative therapies and diagnostics. However, despite these opportunities, only a small fraction of investigational products are successfully developed into cures and therapies that can be accessed by patients. One response to the ever-widening gap between the number and promise of basic scientific discoveries and the translation of those discoveries into therapies is a renewed emphasis on collaborative approaches among federal agencies, academia, and industry, all directed at the advancement of the drug development enterprise. The newly developed Cures Acceleration Network (CAN)-a part of the National Center for Advancing Translational Sciences (NCATS) within the National Institutes of Health (NIH)-has the potential to catalyze widespread changes in NCATS, NIH, and the drug development ecosystem in general. On June 4-5, 2012, the IOM Forum on Drug Discovery, Development, and Translation held, at the request of NCATS, a workshop-bringing together members of federal government agencies, the private sector, academia, and advocacy groups-to explore options and opportunities in the implementation of CAN. Accelerating the Development of New Drugs and Diagnostics: Maximizing the Impact of the Cures Acceleration Network: Workshop Summary summarizes the workshop. Table of ContentsFront Matter1 Introduction2 Approaches to Accelerating Translational Science3 Application of Matching Authority4 Application of Flexible Research Authority5 Situating CAN Within the Drug Development Ecosystem6 Final Reflections on Ways to Maximize the Goals of CANReferencesAppendix A: Workshop AgendaAppendix B: Public Health Service Act, Title IV - National Institutes of HealthAppendix C: Participant Biographies

DKK 266.00
1

Informatics Needs and Challenges in Cancer Research - Board On Health Care Services - Bog - National Academies Press - Plusbog.dk

Informatics Needs and Challenges in Cancer Research - Board On Health Care Services - Bog - National Academies Press - Plusbog.dk

As information technology becomes an integral part of health care, it is important to collect and analyze data in a way that makes the information understandable and useful. Informatics tools—which help collect, organize, and analyze data—are essential to biomedical and health research and development. The field of cancer research is facing an overwhelming deluge of data, heightening the national urgency to find solutions to support and sustain the cancer informatics ecosystem. There is a particular need to integrate research and clinical data to facilitate personalized medicine approaches to cancer prevention and treatment—for example, tailoring treatment based on an individual patient's genetic makeup as well as that of the tumor—and to allow for more rapid learning from patient experiences. To further examine informatics needs and challenges for 21st century biomedical research, the IOM's National Cancer Policy Forum held a workshop February 27-28, 2012. The workshop was designed to raise awareness of the critical and urgent importance of the challenges, gaps and opportunities in informatics; to frame the issues surrounding the development of an integrated system of cancer informatics for acceleration of research; and to discuss solutions for transformation of the cancer informatics enterprise. Informatics Needs and Challenges in Cancer Research: Workshop Summary summarizes the workshop. Table of ContentsFront Matter1 Introduction2 Overview of the Cancer Informatics Landscape3 Informatics and Personalized Medicine4 Informatics-Supported Cancer Research Endeavors5 Potential Pathways and Models for Moving Forward6 Proposal for a Coalition of All Stakeholders7 Transforming Cancer Informatics: From Silos to SystemsAcronymsAppendix A: Workshop AgendaAppendix B: Speaker, Moderator, and Panelist Biographies

DKK 279.00
1

Adapting to Shorter Time Cycles in the United States Air Force - Air Force Studies Board - Bog - National Academies Press - Plusbog.dk

Adapting to Shorter Time Cycles in the United States Air Force - Air Force Studies Board - Bog - National Academies Press - Plusbog.dk

The Air Force Studies Board of the National Academies of Sciences, Engineering, and Medicine hosted a three-part workshop series to investigate the changing paradigm of time and knowledge in modern-day warfare. Sponsored by the U.S. Department of Defense, three 2-day workshops were held virtually on September 16-17, 2020, September 23-24, 2020, and October 1-2, 2020. The objective of the first workshop was to explore the ways in which the U.S. Air Force (USAF) has adjusted its capabilities in response to past shifts in operational timing. In consideration of these past shifts, the second workshop aimed to consider when there could be an advantage to synchronize or desynchronize rates of change with adversaries. Participants had the opportunity to discuss lessons learned and possible changes for USAF Doctrine and future operations. The goal of the third workshop was to examine the implications to doctrine, concepts of operations, and command and control from the recent acceleration of battlespace operations, arising from wide-scale digitization, large-scale sensing, and faster technologies. In all three workshops, speakers explored the broader issues surrounding changing environments, and participants discussed ways to adapt to fundamental changes in the time constants of conflict. This proceedings is a factual summary of what occurred during the workshop series. Table of ContentsFront MatterIntroduction1 Workshop One, Part One2 Workshop One, Part Two3 Workshop Two, Part One4 Workshop Two, Part Two5 Workshop Three, Part One6 Workshop Three, Part TwoAppendixesAppendix A: Statement of TaskAppendix B: Workshop AgendasAppendix C: Biographical Information for Planning Committee MembersAppendix D: Uncertainty, Stability, Instability, Military Affairs, and Time: Some Thoughts and ConjecturesAppendix E: Thoughts and Reactions to Planning Committee DiscussionsAppendix F: E-Mail Commentary on Workshops One and TwoAppendix G: Workshop Series Recap Meeting

DKK 396.00
1

The Flexible Electronics Opportunity - National Research Council - Bog - National Academies Press - Plusbog.dk

The Flexible Electronics Opportunity - National Research Council - Bog - National Academies Press - Plusbog.dk

Flexible electronics describes circuits that can bend and stretch, enabling significant versatility in applications and the prospect of low-cost manufacturing processes. They represent an important technological advance, in terms of their performance characteristics and potential range of applications, ranging from medical care, packaging, lighting and signage, consumer electronics and alternative energy (especially solar energy.) What these technologies have in common is a dependence on efficient manufacturing that currently requires improved technology, processes, tooling, and materials, as well as ongoing research. Seeking to capture the global market opportunity in flexible electronics, major U.S. competitors have initiated dedicated programs that are large in scope and supported with significant government funding to develop and acquire these new technologies, refine them, and ultimately manufacture them within their national borders. These national and regional investments are significantly larger than U.S. investment and more weighted toward later stage applied research and development. The Flexible Electronics Opportunity examines and compares selected innovation programs both foreign and domestic, and their potential to advance the production of flexible electronics technology in the United States. This report reviews the goals, concept, structure, operation, funding levels, and evaluation of foreign programs similar to major U.S. programs, e.g., innovation awards, S&T parks, and consortia. The report describes the transition of flexible electronics research into products and to makes recommendations to improve and to develop U.S. programs. Through an examination of the role of research consortia around the world to advance flexible electronics technology, the report makes recommendations for steps that the U.S. might consider to develop a robust industry in the United States. Significant U.S. expansion in the market for flexible electronics technologies is not likely to occur in the absence of mechanisms to address investment risks, the sharing of intellectual property, and the diverse technology requirements associated with developing and manufacturing flexible electronics technologies. The Flexible Electronics Opportunity makes recommendations for collaboration among industry, universities, and government to achieve the critical levels of investment and the acceleration of new technology development that are needed to catalyze a vibrant flexible electronics industry. Table of ContentsFront MatterExecutive Summary1 Flexible Electronics and the Manufacturing Challenge2 Assessing the Potential of Flexible Electronics3 Government Promotional Efforts4 The Emerging Competitive Landscape5 European Initiatives6 East Asia7 United States8 Findings and RecommendationsBibliography

DKK 396.00
1

Overcoming Barriers to Deployment of Plug-in Electric Vehicles - National Research Council - Bog - National Academies Press - Plusbog.dk

Overcoming Barriers to Deployment of Plug-in Electric Vehicles - National Research Council - Bog - National Academies Press - Plusbog.dk

In the past few years, interest in plug-in electric vehicles (PEVs) has grown. Advances in battery and other technologies, new federal standards for carbon-dioxide emissions and fuel economy, state zero-emission-vehicle requirements, and the current administration's goal of putting millions of alternative-fuel vehicles on the road have all highlighted PEVs as a transportation alternative. Consumers are also beginning to recognize the advantages of PEVs over conventional vehicles, such as lower operating costs, smoother operation, and better acceleration; the ability to fuel up at home; and zero tailpipe emissions when the vehicle operates solely on its battery. There are, however, barriers to PEV deployment, including the vehicle cost, the short all-electric driving range, the long battery charging time, uncertainties about battery life, the few choices of vehicle models, and the need for a charging infrastructure to support PEVs. What should industry do to improve the performance of PEVs and make them more attractive to consumers?At the request of Congress, Overcoming Barriers to Deployment of Plug-in Electric Vehicles identifies barriers to the introduction of electric vehicles and recommends ways to mitigate these barriers. This report examines the characteristics and capabilities of electric vehicle technologies, such as cost, performance, range, safety, and durability, and assesses how these factors might create barriers to widespread deployment. Overcoming Barriers to Deployment of Plug-in Electric Vehicles provides an overview of the current status of PEVs and makes recommendations to spur the industry and increase the attractiveness of this promising technology for consumers. Through consideration of consumer behaviors, tax incentives, business models, incentive programs, and infrastructure needs, this book studies the state of the industry and makes recommendations to further its development and acceptance. Table of ContentsFront MatterSummary1 Introduction2 Plug-in Electric Vehicles and Charging Technologies3 Understanding the Customer Purchase and Market Development Process for Plug-in Electric Vehicles4 Government Support for Deployment of Plug-in Electric Vehicles5 Charging Infrastructure for Plug-in Electric Vehicles6 Implications of Plug-in Electric Vehicles for the Electricity Sector7 Incentives for the Deployment of Plug-in Electric VehiclesAppendixesAppendix A: Biographical Information on the Committee on Overcoming Barriers to Electric-Vehicle DeploymentAppendix B: Meetings and PresentationsAppendix C: International Incentives

DKK 370.00
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